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KidsMatter is underpinned by a body of leading national and international research, expert opinion, and experience in the field of children’s mental health and wellbeing, early childhood and education. This evidence-base approach incorporates a risk and protective factors framework for children’s mental health, a socio-ecological model of child development, and whole-school or service approach to mental health. 
Flinders University has conducted research on KidsMatter Primary, which has shown the initiative to be effective in improving children’s mental health and their ability to learn.